IntroductionIndole-3-carbinol (I3C) is found in cruciferous vegetables and used as a dietary supplement.It is known to act as a ligand for aryl hydrocarbon receptor (AhR).In the current study, we investigated the role of AhR and the ability of I3C to attenuate LPS-induced Acute Respiratory Distress Syndrome (ARDS).MethodsTo that end, we induced ARD

Chronic stress has an important impact on the adult brain.However, most of the knowledge on its effects is focused on principal neurons and less on inhibitory neurons.Consequently, recent reports have begun to describe stress-induced alterations in the structure, connectivity and neurochemistry of interneurons.Some of these changes appear to be med

Background:.Although indocyanine-green fluorescence angiography (ICG-FA) has been established as a useful tool to assess perfusion in free tissue transfer, only few studies have applied this modality to pedicled perforator flaps.As both volume and reach of pedicled perforator flaps are limited and tip necrosis often equals complete flap failure, IC

ABSTRACT In the United States, humans spend the majority of their time indoors, where they are exposed to the microbiome of the built environment (BE) they inhabit.Despite the ubiquity of microbes in BEs and their potential impacts on health and building materials, basic questions about the microbiology of these environments remain unanswered.We pr

Background: C-reactive protein (CRP) participates in development of inflammatory diseases.Hepatocytes are a major contributor of circulating CRP.Although angiotensin II (Ang II) is known to evoke inflammatory response, it remains unknown whether Ang II induces CRP expression in hepatocytes.The present study observed effect of Ang II on CRP expressi